WEP 2019 Opening Keynote: Paolo Sassone-Corsi

Time of Your Life: You Are What You Eat (and When!)

The circadian clock is an endogenous, time-tracking system that directs multiple metabolic and physiological functions required for homeostasis. The master clock located within the suprachiasmatic nucleus (SCN) in the hypothalamus operates as an 'orchestra director' for peripheral clocks present in all systemic tissues, contributing to their alignment and ultimately to temporal coordination of physiology. Accumulating evidence reveals coordination and communications between clocks and their alteration under nutritional challenges. The molecular language of these regulatory pathways implicates the interplay between metabolic cycles and epigenetic control.

WEP 2019 Opening Keynote: Paolo Sassone-Corsi researchers have extended the life of a human cell by
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